Ionis Pharmaceuticals, Inc. (IONS) /
The profitability of Ionis Pharmaceuticals, Inc. over the past 10 years
Chart Ionis Pharmaceuticals, Inc.: gross profit, operating income, net income, fiscal 2016–2025 Open the chart →Ionis Pharmaceuticals, Inc. reported a net loss of $381.39M in fiscal 2025, the latest fiscal year on file. That year it had gross profit of $927.8M and an operating loss of $381.68M. It reported a profit in 3 of the 10 years shown, and a loss in fiscal 2016, 2020, 2021, 2022, 2023, 2024 and 2025. Its highest net income in these years was $278.14M, in fiscal 2019.
Year by year
| Fiscal year | Gross profit | Operating income | Net income |
|---|---|---|---|
| 2025ended Dec 31, 2025 | $927.8M* | -$381.68M | -$381.39M |
| 2024ended Dec 31, 2024 | $693.92M* | -$475.08M | -$453.9M |
| 2023ended Dec 31, 2023 | $778.51M* | -$353.73M | -$366.29M |
| 2022ended Dec 31, 2022 | $573.25M* | -$410.19M | -$269.72M |
| 2021ended Dec 31, 2021 | $799.61M* | -$30.19M | -$28.6M |
| 2020ended Dec 31, 2020 | $717.32M* | -$172.08M | -$444.26M |
| 2019ended Dec 31, 2019 | $1.12B* | $365.88M | $278.14M |
| 2018ended Dec 31, 2018 | $597.85M* | -$61.37M | $273.74M |
| 2017ended Dec 31, 2017 | $514.18M* | $31.05M | $346K |
| 2016ended Dec 31, 2016 | $372.78M* | -$20.16M | -$60.4M |
Fiscal years as Ionis Pharmaceuticals, Inc. reports them. * Calculated by us from the company's filed figures; — no figure on file. From SEC filings, updated nightly. How each line is read.
More on Ionis Pharmaceuticals, Inc.
- The revenue of Ionis Pharmaceuticals, Inc.
- The cash flow of Ionis Pharmaceuticals, Inc.
- The debt of Ionis Pharmaceuticals, Inc.
- All of Ionis Pharmaceuticals, Inc.'s financials, charted
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Not investment advice. This page shows what Ionis Pharmaceuticals, Inc. filed with the SEC. Nothing here is a recommendation about any security. Check important figures against the company's own filings.