Ionis Pharmaceuticals, Inc. (IONS) /

The cash flow of Ionis Pharmaceuticals, Inc. over the past 10 years

Chart Ionis Pharmaceuticals, Inc.: operating cash flow, capital expenditures, free cash flow, fiscal 2016–2025 Open the chart →

In fiscal 2025, the latest fiscal year on file, Ionis Pharmaceuticals, Inc.'s operating cash flow was -$268.58M and its capital expenditures $51.44M, leaving free cash flow of -$320.03M. Free cash flow was above zero in 5 of the 10 years shown. It ranged from -$546.23M in fiscal 2024 to $585.25M in fiscal 2018. Capital expenditures were highest in fiscal 2025, at $51.44M.

Year by year

Fiscal yearOperating cash flowCapital expendituresFree cash flow*
2025ended Dec 31, 2025-$268.58M$51.44M-$320.03M
2024ended Dec 31, 2024-$500.95M$45.28M-$546.23M
2023ended Dec 31, 2023-$307.51M$23.8M-$331.32M
2022ended Dec 31, 2022-$274.37M$15.72M-$290.09M
2021ended Dec 31, 2021$30.8M$11.96M$18.84M
2020ended Dec 31, 2020$35.89M$35.12M$772K
2019ended Dec 31, 2019$345.63M$30.91M$314.72M
2018ended Dec 31, 2018$602.91M$17.65M*$585.25M
2017ended Dec 31, 2017$174.15M$34.76M$139.38M
2016ended Dec 31, 2016-$112.11M$7.11M-$119.21M

Fiscal years as Ionis Pharmaceuticals, Inc. reports them. * Calculated by us from the company's filed figures; — no figure on file. From SEC filings, updated nightly. How each line is read.

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Not investment advice. This page shows what Ionis Pharmaceuticals, Inc. filed with the SEC. Nothing here is a recommendation about any security. Check important figures against the company's own filings.